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BDBM50003501 3,3-Diphenyl-1-[4-(pyridin-3-ylamino)-piperidin-1-yl]-propan-1-one; dihydrochloride; hydrate::CHEMBL3216628::CHEMBL545536

SMILES: Cl.Cl.O=C(CC(c1ccccc1)c1ccccc1)N1CCC(CC1)Nc1cccnc1

InChI Key: InChIKey=ZJKWHHHHZUOJLU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003501   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003501
PNG
(3,3-Diphenyl-1-[4-(pyridin-3-ylamino)-piperidin-1-...)
Show SMILES Cl.Cl.O=C(CC(c1ccccc1)c1ccccc1)N1CCC(CC1)Nc1cccnc1
Show InChI InChI=1S/C25H27N3O/c29-25(28-16-13-22(14-17-28)27-23-12-7-15-26-19-23)18-24(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-12,15,19,22,24,27H,13-14,16-18H2
MMDB

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Similars

Article
PubMed
n/an/a 87n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair