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BDBM50003529 (4-{2-[Methyl-(3-phenyl-propyl)-amino]-acetyl}-piperazin-1-yl)-pyridin-3-yl-acetonitrile; dihydrochloride; hydrate::CHEMBL3216385::CHEMBL554462

SMILES: Cl.Cl.CN(CCCc1ccccc1)CC(=O)N1CCN(CC1)C(C#N)c1cccnc1

InChI Key: InChIKey=OGOZMPDBVZGMBB-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003529   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003529
PNG
((4-{2-[Methyl-(3-phenyl-propyl)-amino]-acetyl}-pip...)
Show SMILES Cl.Cl.CN(CCCc1ccccc1)CC(=O)N1CCN(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C23H29N5O/c1-26(12-6-9-20-7-3-2-4-8-20)19-23(29)28-15-13-27(14-16-28)22(17-24)21-10-5-11-25-18-21/h2-5,7-8,10-11,18,22H,6,9,12-16,19H2,1H3
MMDB

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Similars

Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair