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BDBM50003536 (1-Diphenylacetyl-piperidin-4-yl)-pyridin-3-yl-acetonitrile::CHEMBL340544

SMILES: O=C(C(c1ccccc1)c1ccccc1)N1CCC(CC1)C(C#N)c1cccnc1

InChI Key: InChIKey=DBKJBAQPDMQAHQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003536   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003536
PNG
((1-Diphenylacetyl-piperidin-4-yl)-pyridin-3-yl-ace...)
Show SMILES O=C(C(c1ccccc1)c1ccccc1)N1CCC(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C26H25N3O/c27-18-24(23-12-7-15-28-19-23)20-13-16-29(17-14-20)26(30)25(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-12,15,19-20,24-25H,13-14,16-17H2
MMDB

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Article
PubMed
n/an/a 21n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair