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BDBM50003625 CHEMBL490237

SMILES: [Br-].OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOCc3ccccc3F)(CC1)CC2

InChI Key: InChIKey=YTIXDYJVHDWDOY-UHFFFAOYSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003625   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50003625
PNG
(CHEMBL490237)
Show SMILES [Br-].OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOCc3ccccc3F)(CC1)CC2
Show InChI InChI=1S/C29H33FNO2.BrH/c30-27-14-8-7-9-24(27)23-33-22-21-31-18-15-28(16-19-31,17-20-31)29(32,25-10-3-1-4-11-25)26-12-5-2-6-13-26;/h1-14,32H,15-23H2;1H/q+1;/p-1
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Similars

Article
PubMed
n/an/a<1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...


J Med Chem 52: 2493-505 (2009)


Article DOI: 10.1021/jm801601v
BindingDB Entry DOI: 10.7270/Q2H131X8
More data for this
Ligand-Target Pair