BDBM67690 1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis(oxidanyl)anthracene-9,10-dione;hydrochloride::1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-9,10-anthraquinone;hydrochloride::1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;hydrochloride::DHAD::MITOXANTRONE::MITOXANTRONE DIHYDROCHLORIDE::MLS001333711::SMR000058480::cid_4212::cid_5458171

SMILES: c1cc(c2c(c1NCCNCCO)C(=O)c3c(ccc(c3C2=O)O)O)NCCNCCO

InChI Key: InChIKey=KKZJGLLVHKMTCM-UHFFFAOYSA-N

Data: 2 KI  27 IC50  4 EC50

PDB links: 8 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 67690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein LANA1 (HHV-8)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.69E+3	n/a	n/a	n/a	n/a
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DNA-3-methyladenine glycosylase (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 3 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance-associated protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance-associated protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance-associated protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	904	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 33 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.88E+3	n/a	n/a	n/a	n/a
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Group 3 secretory phospholipase A2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Group 3 secretory phospholipase A2 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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NEDD8-activating enzyme E1 catalytic subunit (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
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DNA-(apurinic or apyrimidinic site) endonuclease (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance-associated protein 1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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TAR DNA-binding protein 43 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA topoisomerase 2-alpha (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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P2Y purinoceptor 12 (Human)	BDBM67690 (SMR000058480 | DHAD | 1,4-bis[2-(2-hydroxyethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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