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BDBM50003720 CHEMBL3235286

SMILES: CNc1ncnc2OCC(=Nc12)c1ccc(Br)cc1

InChI Key: InChIKey=JMRXWGJGKMUMHQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003720   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 1 (DGAT1)


(Homo sapiens (Human))
BDBM50003720
PNG
(CHEMBL3235286)
Show SMILES CNc1ncnc2OCC(=Nc12)c1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrN4O/c1-15-12-11-13(17-7-16-12)19-6-10(18-11)8-2-4-9(14)5-3-8/h2-5,7H,6H2,1H3,(H,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPA


J Med Chem 57: 3464-83 (2014)


Article DOI: 10.1021/jm500135c
BindingDB Entry DOI: 10.7270/Q23X886W
More data for this
Ligand-Target Pair