BDBM50003737 (Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylene-2-oxo-tetrahydro-pyran-3-yl]-benzamide::CHEMBL135724

SMILES [#7]\[#6](-[#7])=[#7]\c1ccc(cc1)-[#6]-1-[#6]\[#6](-[#8]-[#6](=O)-[#6]-1-[#7]-[#6](=O)-c1ccccc1)=[#6]\I

InChI Key InChIKey=XDKMLHUPRBBCGK-PTNGSMBKSA-N

Data  4 KI  2 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50003737   

TargetChymotrypsinogen A(Bos taurus (bovine))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKi:  170nMAssay Description:Compound was tested for its binding affinity against the enzyme alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKi:  670nMAssay Description:Compound was tested for its binding affinity against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKi:  670nMAssay Description:Compound was tested for its binding affinity against the enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKi:  1.87E+4nMAssay Description:Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKon:  0.0000130M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50003737((Lactone4)N-[4-(4-Guanidino-phenyl)-6-iodomethylen...)
Affinity DataKon:  0.0000830M-1s-1Assay Description:Compound was tested for the rate constant of deacylation against the enzyme Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed