BDBM50003824 6-[4,5-Bis-(3-methoxy-phenyl)-1H-imidazol-2-ylsulfanylmethyl]-4-hydroxy-4-methyl-tetrahydro-pyran-2-one::CHEMBL423351

SMILES COc1cccc(c1)-c1nc(SCC2C[C@](C)(O)CC(=O)O2)[nH]c1-c1cccc(OC)c1

InChI Key InChIKey=FCSIECLFLLQTBR-WIIYFNMSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003824   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003824(6-[4,5-Bis-(3-methoxy-phenyl)-1H-imidazol-2-ylsulf...)
Affinity DataIC50:  570nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed