BindingDB PrimarySearch

BDBM50004000 (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate::Antilirium::CHEMBL94::Eserine::Physostol::physostigmine

SMILES: CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1

InChI Key: InChIKey=PIJVFDBKTWXHHD-UHFFFAOYSA-N

Data: 4 KI 130 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 135 hits for monomerid = 50004000
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxylic ester hydrolase (Rat)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Mouse)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Mouse)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47.2	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Rat)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
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Carboxylic ester hydrolase (Horse)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Cholinesterase (Horse)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	27.9	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Bovine)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Pacific electric ray)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	538	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50004000 (CHEMBL94 \| physostigmine \| Antilirium \| Eserine \| ...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
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