BDBM50004051 2-Amino-4-phosphono-butyric acid::2-Amino-4-phosphono-butyric acid (AP4)::4-Amino Phosphonobutyrate::CHEMBL285843::GlcN-6-P synthase inhibitor, 1 (racemic mixture)::L-AP4

SMILES NC(CCP(O)(O)=O)C(O)=O

InChI Key InChIKey=DDOQBQRIEWHWBT-UHFFFAOYSA-N

Data  14 KI  2 IC50  3 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50004051   

TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  680nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  1.26E+3nMMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--fructose-6-phosphate aminotransferase [isomerizing](Candida albicans)
Technical University Of Gdansk

LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataKi:  1.20E+7nM IC50:  2.60E+7nMpH: 6.85Assay Description:Two assays of GlcN-6-P synthase activity were used 1)determination of GlcN-6_P formation by the modified Elson-Morgan procedure and 2) continuous qua...More data for this Ligand-Target Pair
In DepthDetails
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  1.00E+3nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails Article
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8More data for this Ligand-Target Pair