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BDBM50004086 CHEMBL3236112

SMILES: NC[C@H]1CN(C(=O)C[C@@H]1c1cc(F)ccc1F)c1ccc2ccccc2n1

InChI Key: InChIKey=OAQMJHUCAUVBIT-VTLFJGNJNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004086   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50004086
PNG
(CHEMBL3236112)
Show SMILES NC[C@H]1CN(C(=O)C[C@@H]1c1cc(F)ccc1F)c1ccc2ccccc2n1
Show InChI InChI=1/C21H19F2N3O/c22-15-6-7-18(23)17(9-15)16-10-21(27)26(12-14(16)11-24)20-8-5-13-3-1-2-4-19(13)25-20/h1-9,14,16H,10-12,24H2/t14-,16-/s2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.03E+3n/an/an/an/an/an/a



M.S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis


Bioorg Med Chem Lett 24: 1918-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.009
BindingDB Entry DOI: 10.7270/Q2G73G7F
More data for this
Ligand-Target Pair