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BDBM50004093 CHEMBL3236116

SMILES: NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1cc(F)ccc1F

InChI Key: InChIKey=WMZXPXIZBXCOTD-VTLFJGNJNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004093   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50004093
PNG
(CHEMBL3236116)
Show SMILES NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1cc(F)ccc1F
Show InChI InChI=1/C19H21F2N3O/c20-15-1-2-18(21)17(9-15)16-10-19(25)24(12-14(16)11-22)8-5-13-3-6-23-7-4-13/h1-4,6-7,9,14,16H,5,8,10-12,22H2/t14-,16-/s2
PDB
MMDB

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Similars

Article
PubMed
n/an/a 84n/an/an/an/an/an/a



M.S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis


Bioorg Med Chem Lett 24: 1918-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.009
BindingDB Entry DOI: 10.7270/Q2G73G7F
More data for this
Ligand-Target Pair