BDBM50004108 (+-)-nicotine::(R,S)-nicotine::(RS)-nicotine::3-(1-methylpyrrolidin-2-yl)pyridine::CHEMBL440464::Nicotin::Nicotine-(+)::Nikotin::US11667638, Example Nicotine::US8609708, 54 Nicotine::US9284322, Nicotine::US9993465, Nicotine::nicotine

SMILES: C[N@@]1CCC[C@H]1c2cccnc2

InChI Key: InChIKey=SNICXCGAKADSCV-UHFFFAOYSA-N

Data: 83 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 86 hits for monomerid = 50004108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)/Neuronal acetylcholine receptor subunit beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	-12.0	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		7.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-6 (Chicken)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		26.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		55.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		55.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholine-binding protein (Great pond snail)	BDBM50004108 ((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...) Show SMILES Show InChI	GoogleScholar	UniChem		83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair