BDBM50004152 (HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylsulfanyl-1H-pyrimidine-2,4-dione::1-((2-hydroxyethoxy)methyl)-5-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione::1-(2-HYDROXYETHYLOXYMETHYL)-6-PHENYL THIOTHYMINE::1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylsulfanyl-1H-pyrimidine-2,4-dione::1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-phenylsulfanyl-1H-pyrimidine-2,4-dione(HEPT)::1-[(2-hydroxyethoxy)methyl]-6-(phenylsulfanyl)thymine::1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)-thymine::CHEMBL31871

SMILES: CC1=C(N(C(=O)NC1=O)COCCO)Sc2ccccc2

InChI Key: InChIKey=HDMHBHNRWDNNCD-UHFFFAOYSA-N

Data: 8 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50004152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50004152 (CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair