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BDBM50004268 2-Oxo-1-propyl-1,2-dihydro-quinoline-4-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::CHEMBL325349

SMILES: CCCn1c2ccccc2c(cc1=O)C(=O)OC1CC2CCC(C1)N2C

InChI Key: InChIKey=RTTZOQDXXOWLHF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50004268
PNG
(2-Oxo-1-propyl-1,2-dihydro-quinoline-4-carboxylic ...)
Show SMILES CCCn1c2ccccc2c(cc1=O)C(=O)OC1CC2CCC(C1)N2C
Show InChI InChI=1S/C21H26N2O3/c1-3-10-23-19-7-5-4-6-17(19)18(13-20(23)24)21(25)26-16-11-14-8-9-15(12-16)22(14)2/h4-7,13-16H,3,8-12H2,1-2H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.450n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co.

Curated by ChEMBL


Assay Description
Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.


J Med Chem 35: 4893-902 (1992)


Article DOI: 10.1021/jm00104a016
BindingDB Entry DOI: 10.7270/Q2BK1CZ2
More data for this
Ligand-Target Pair