BDBM50004310 1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL267795

SMILES Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccccc12

InChI Key InChIKey=GHAMYXPEZSUOCU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50004310   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50004310(1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin...)
Affinity DataIC50:  930nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50004310(1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50004310(1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin...)
Affinity DataIC50:  33nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50004310(1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed