BDBM50004665 (oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one::1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one::1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one (oxotremorphine)::1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one(Oxotremorine)::1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidinium::CHEMBL7634::Oxotremorine::Oxotremorine1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one::cid_4630

SMILES: O=C1CCCN1CC#CCN1CCCC1

InChI Key: InChIKey=RSDOPYMFZBJHRL-UHFFFAOYSA-N

Data: 50 KI  25 IC50  2 Kd  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 89 hits for monomerid = 50004665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mucolipin-3 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	858	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	364	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Mouse)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ion channel NompC (Zebrafish)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Guinea pig)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Guinea pig)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Human)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mouse)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Mouse)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50004665 (1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidi...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair