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BDBM50004905 CHEMBL2376449

SMILES: Cc1cccc(c1)N1CCN(Cc2ccccc2-c2ccccc2)CC1

InChI Key: InChIKey=PPTNARLFCSSMOS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50004905
PNG
(CHEMBL2376449)
Show SMILES Cc1cccc(c1)N1CCN(Cc2ccccc2-c2ccccc2)CC1
Show InChI InChI=1S/C24H26N2/c1-20-8-7-12-23(18-20)26-16-14-25(15-17-26)19-22-11-5-6-13-24(22)21-9-3-2-4-10-21/h2-13,18H,14-17,19H2,1H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells


Bioorg Med Chem 21: 2568-76 (2013)


Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50004905
PNG
(CHEMBL2376449)
Show SMILES Cc1cccc(c1)N1CCN(Cc2ccccc2-c2ccccc2)CC1
Show InChI InChI=1S/C24H26N2/c1-20-8-7-12-23(18-20)26-16-14-25(15-17-26)19-22-11-5-6-13-24(22)21-9-3-2-4-10-21/h2-13,18H,14-17,19H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells


Bioorg Med Chem 21: 2568-76 (2013)


Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC
More data for this
Ligand-Target Pair