BDBM50004917 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Cl-APB)::CHEMBL35354::CHEMBL544115::RS(+/-)-6-Cl-APB3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SKF 82958

SMILES Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1

InChI Key InChIKey=HJWHHQIVUHOBQN-UHFFFAOYSA-N

Data  15 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50004917   

TargetD(1A) dopamine receptor(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  4.56nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  5.5nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  22nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  68nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  77.3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  136nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  264nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  558nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.30E+3nMAssay Description:The compound was evaluated for the binding affinity towards Dopamine receptor D2 at low affinity stateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.30E+3nMAssay Description:The compound was evaluated for the binding affinity towards Dopamine receptor D2 at low affinity stateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.61E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.78E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  4.63E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataIC50:  336nMAssay Description:Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataEC50:  0.730nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as reversal of Ro 20-1724 mediated decrease in cAMP accumulation aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as assessed as increase in beta-arrestin-2 recruitment after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50004917(3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed