BDBM50004922 3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Br-APB)::CHEMBL32145::CHEMBL544114::RS-(+/-)-6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol

SMILES Oc1cc2C(CN(CC=C)CCc2c(Br)c1O)c1ccccc1

InChI Key InChIKey=KKZGFVAZUKHFAC-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004922   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004922(3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataKi:  5nMAssay Description:The compound was evaluated for the dissociation constant for inhibiting the binding of [3H]-SCH- 23390 at dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004922(3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataKi:  19nMAssay Description:The compound was evaluated for the binding affinity towards Dopamine receptor D2 at low affinity stateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50004922(3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataKi:  2.10E+4nMAssay Description:The compound was evaluated for the binding affinity towards dopamine receptor D2 at low affinity state.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50004922(3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50004922(3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  701nMAssay Description:Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed