BDBM50004938 3-Carboxymethylsulfanyl-4,6-dichloro-1H-indole-2-carboxylic acid::CHEMBL300949

SMILES OC(=O)CSc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O

InChI Key InChIKey=IUHDRDDTXVMFIA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004938   

LigandPNGBDBM50004938(3-Carboxymethylsulfanyl-4,6-dichloro-1H-indole-2-c...)
Affinity DataIC50:  100nMAssay Description:Ability of compound to compete with [3H]-glycine for the strychnine-insensitive NMDA receptor glycine binding sites on rat cortical and hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004938(3-Carboxymethylsulfanyl-4,6-dichloro-1H-indole-2-c...)
Affinity DataEC50:  1.40E+5nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed