BDBM50005132 4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione::4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione (Gepirone)::CHEMBL1204187::CHEMBL284092::GEPIRONE::gepiron ER

SMILES: CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C1

InChI Key: InChIKey=QOIGKGMMAGJZNZ-UHFFFAOYSA-N

Data: 9 KI  5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50005132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		4.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50005132 (4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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