BDBM50005313 CHEMBL169718::{2-[1-(4-Butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-pentyl]-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl}-carbamic acid tert-butyl ester;0.2H2O

SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCC)N1Cc2ccccc2C[C@H](NC(=O)OC(C)(C)C)C1=O)C(C)C

InChI Key InChIKey=QKVZJSLSRUHSPD-ZZTWKDBPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005313   

TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005313(CHEMBL169718 | {2-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  1.73E+3nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed