BDBM50005536 42-548::5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol::5-(4-chlorophenyl)-3,5-dihydro-2H-imidazo[2,1-a]isoindol-5-ol::5-Thiophen-2-yl-2,3,5,6-tetrahydro-imidazo[2,1-a]isoquinolin-5-ol::CHEMBL781::MAZINDOL::Mazanor::Sanorex::mazindole

SMILES: c1ccc2c(c1)C3=NCCN3[C@]2(c4ccc(cc4)Cl)O

InChI Key: InChIKey=ZPXSCAKFGYXMGA-UHFFFAOYSA-N

Data: 44 KI  29 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 74 hits for monomerid = 50005536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Mouse)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		2.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Norepinephrine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rat)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		14.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		15.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM50005536 (Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...) Show SMILES Show InChI	GoogleScholar	UniChem		22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair