BDBM50005834 1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-acetyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL38041

SMILES CC(C)n1c2ccccc2n(C(=O)CC2CC3CCC(C2)N3C)c1=O

InChI Key InChIKey=DKNCSSURJOYOSO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50005834   

Target5-hydroxytryptamine receptor 1A/1B/1D/1F(RAT)
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]5-HT binding to 5-hydroxytryptamine 1 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat whole brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]rauwolscine binding to alpha-2 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]domperidone binding to dopamine receptor D2 in rat striataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]dihydroalprenolol prenolol binding to Beta adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50005834(1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi: >1.00E+4nMAssay Description:The ability to inhibit [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain corticesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed