BDBM50005849 CHEMBL290715::spiro[4-azabicyclo[2.2.2]octane-2,4'-[1,3]dioxolane]

SMILES C1OCC2(CN3CCC2CC3)O1

InChI Key InChIKey=UFKMZGGTOQBHQL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005849   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  1.90E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M1 in guinea pig cerebral cortex using (-)-[3H]-QNB as radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  5.00E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M2 in guinea pig heart using (-)-[3H]-QNB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor(Cavia porcellus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50005849(CHEMBL290715 | spiro[4-azabicyclo[2.2.2]octane-2,4...)
Affinity DataKi:  8.60E+4nMAssay Description:Compound was evaluated for its binding affinity against muscarinic acetylcholine receptor M3 in guinea pig parotid gland using (-)-[3H]-QNB as radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed