BDBM50006327 6-Carboxymethyl-12-(3-guanidino-propyl)-15-isopropyl-1,5,8,11,14,17-hexaoxo-1lambda*4*-thia-4,7,10,13,16-pentaaza-cyclooctadecane-3-carboxylic acid::CHEMBL293214

SMILES CC(C)[C@@H]1NC(=O)CS(=O)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O

InChI Key InChIKey=GPYDNKNVGLPQHE-BETHWKPISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006327   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  210nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  2.90nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  210nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed