BDBM50006411 CHEMBL2367470::Sodium; 7-[5-(4-fluoro-phenyl)-1-pyridin-2-yl-3-trifluoromethyl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate

SMILES [Na+].O[C@H](C[C@H](O)\C=C\c1c(nn(c1-c1ccc(F)cc1)-c1ccccn1)C(F)(F)F)CC([O-])=O

InChI Key InChIKey=JHXBJZCJRXLNJA-ZRRIJIRJSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006411   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006411(CHEMBL2367470 | Sodium; 7-[5-(4-fluoro-phenyl)-1-p...)
Affinity DataIC50:  17nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed