BDBM50006469 CHEMBL69956::[8-Oxo-7-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-7,8-dihydro-pyrido[2,3-d]pyridazin-5-yl]-acetic acid

SMILES OC(=O)Cc1nn(Cc2nc3cc(ccc3s2)C(F)(F)F)c(=O)c2ncccc12

InChI Key InChIKey=BWGDCBBYQOFUJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006469   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006469(CHEMBL69956 | [8-Oxo-7-(5-trifluoromethyl-benzothi...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human Aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Y. B. Chavan College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50006469(CHEMBL69956 | [8-Oxo-7-(5-trifluoromethyl-benzothi...)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed