BDBM50006677 1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl]-benzene::1,2,3-Trimethoxy-5-[2-(4-methoxy-phenyl)-vinyl]-benzene::10Z-3,4,4',5-tetramethoxystilbene::3,4,4',5-tetramethoxy-(Z)-stilbene::5-(4-methoxystyryl)-1,2,3-trimethoxybenzene::CHEMBL47426::Trans-1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)-vinyl]-benzene (13)

SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1

InChI Key InChIKey=GGFQQRXTLIJXNY-WAYWQWQTSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006677   

TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Concentration required to inhibit polymerization of tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was tested for the concentration to inhibit 50% of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Arizona State University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1/Tubulin beta-2B chain(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL
LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50:  200nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed