BDBM50006789 CHEMBL3236549

SMILES CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1

InChI Key InChIKey=COOGVHJHSCBOQT-MRVPVSSYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50006789   

TargetHistamine H4 receptor(Mus musculus (mouse))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]histamine from mouse recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]histamine from mouse histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]histamine from rat histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]histamine from rat recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H4(GUINEA PIG)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  306nMAssay Description:Binding affinity to guinea pig histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine receptor H4(GUINEA PIG)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  306nMAssay Description:Displacement of [3H]histamine from guinea pig recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in SK-N-MC cells after 45 mins by competition bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi: >1.00E+4nMAssay Description:Agonist activity at human H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed