BDBM50007300 CHEMBL2367827::Sodium; 7-[2-(4-fluoro-phenyl)-4-methyl-6-phenyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate

SMILES [Na+].Cc1cc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1

InChI Key InChIKey=YNQVGZUDNRAWKS-JUGDMTMFSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007300   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007300(CHEMBL2367827 | Sodium; 7-[2-(4-fluoro-phenyl)-4-m...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of solubilized HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed