BDBM50007406 1-(3-(trifluoromethyl)phenyl)piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine(TFMPP)::CHEMBL274866::TFMPP

SMILES: FC(F)(F)c1cccc(c1)N1CCNCC1

InChI Key: InChIKey=KKIMDKMETPPURN-UHFFFAOYSA-N

Data: 70 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 76 hits for monomerid = 50007406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		12.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		27.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		39.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		55.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		58.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		58.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		60.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		64.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		74.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		84.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		85.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Dog)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rabbit)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine 1D receptor (Bovine)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		163	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		174	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine 1D receptor (Bovine)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50007406 (TFMPP | 1-(3-(trifluoromethyl)phenyl)piperazine | ...) Show SMILES Show InChI	GoogleScholar	UniChem		288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair