BDBM50007472 1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-cyclohexyl]-ethanone::CHEMBL341584

SMILES CC(=O)C1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12

InChI Key InChIKey=RYHBLWVQRUGERI-PGMHBOJBSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007472   

TargetHistamine H1 receptor(RAT)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007472(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007472(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed