BDBM50007476 4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,2-diol::CHEMBL266619

SMILES CC(C)(C)NCC(O)COc1ccc(O)c(O)c1

InChI Key InChIKey=GWXLUBAMOLHDHG-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007476   

TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataKi:  120nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  8.20nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  130nMAssay Description:Agonistic activity (beta2- adrenergic) for the percent maximal relaxation of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(GUINEA PIG)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  4.70nMAssay Description:Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atriaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed