BDBM50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R

SMILES: CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12

InChI Key: InChIKey=XRYLGRGAWQSVQW-UHFFFAOYSA-N

Data: 20 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50007567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Golden hamster)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Bovine)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Golden hamster)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Bovine)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dopamine receptor D4 (Dog)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dopamine receptor D4 (Dog)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM50007567 (CHEMBL64875 | OCTOCLOTHEPIN-R | 1-(8-Chloro-10,11-...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair