BDBM50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE

SMILES: O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12

InChI Key: InChIKey=ZFZPJDFBJFHYIV-UHFFFAOYSA-N

Data: 19 KI  13 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 50007692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.334	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.963	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 3 (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		9.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		13.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50007692 (TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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