BDBM50008161 5-Cyclohexyl-2,2-difluoro-3-hydroxy-4-{2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoylamino}-pentanoic acid ethyl ester; (CH3)2NCHO::CHEMBL284922

SMILES CCOC(=O)C(F)(F)C(O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

InChI Key InChIKey=RMVGKCQDVNQSGV-QPWGPPCNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008161   

TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008161(5-Cyclohexyl-2,2-difluoro-3-hydroxy-4-{2-[2-(morph...)
Affinity DataIC50:  767nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008161(5-Cyclohexyl-2,2-difluoro-3-hydroxy-4-{2-[2-(morph...)
Affinity DataIC50:  1.90nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed