BDBM50008162 CHEMBL31621::N-[1-Cyclohexylmethyl-3,3-difluoro-3-(2-morpholin-4-yl-ethylcarbamoyl)-2-oxo-propyl]-2-[2-(morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-malonamic acid methyl ester; Hydrate

SMILES COC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)C(=O)NCCN1CCOCC1

InChI Key InChIKey=ILVIKHFAJWQSOQ-HZFUHODCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008162   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008162(CHEMBL31621 | N-[1-Cyclohexylmethyl-3,3-difluoro-3...)
Affinity DataIC50:  0.790nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008162(CHEMBL31621 | N-[1-Cyclohexylmethyl-3,3-difluoro-3...)
Affinity DataIC50:  515nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed