BDBM50008172 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichloro-benzoylamino)-butyric acid::CHEMBL340413

SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1

InChI Key InChIKey=COZGZMCLUAHPHG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008172   

TargetGastrin/cholecystokinin type B receptor(RAT)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008172(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichl...)
Affinity DataIC50:  600nMAssay Description:Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008172(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichl...)
Affinity DataIC50:  1.35E+4nMAssay Description:Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic aciniMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008172(4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3,5-dichl...)
Affinity DataIC50:  200nMAssay Description:Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to CCK-B in rabbit gastric glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed