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BDBM50008550 6-Methyl-6,7-dihydro-indeno[5,6-d][1,3]dioxol-5-one::CHEMBL422695

SMILES: CC1Cc2cc3OCOc3cc2C1=O

InChI Key: InChIKey=ZSOHEKFEVDPZKH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008550   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Homo sapiens (human))
BDBM50008550
PNG
(6-Methyl-6,7-dihydro-indeno[5,6-d][1,3]dioxol-5-on...)
Show SMILES CC1Cc2cc3OCOc3cc2C1=O
Show InChI InChI=1S/C11H10O3/c1-6-2-7-3-9-10(14-5-13-9)4-8(7)11(6)12/h3-4,6H,2,5H2,1H3
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



University of Illinois

Curated by ChEMBL


Assay Description
IC50 against acetylcholinesterase; value ranges from 1.3-380 nM.


J Med Chem 35: 584-9 (1992)


Article DOI: 10.1021/jm00081a022
BindingDB Entry DOI: 10.7270/Q20G3J3J
More data for this
Ligand-Target Pair
Cholinesterases; ACHE & BCHE


(Homo sapiens (human))
BDBM50008550
PNG
(6-Methyl-6,7-dihydro-indeno[5,6-d][1,3]dioxol-5-on...)
Show SMILES CC1Cc2cc3OCOc3cc2C1=O
Show InChI InChI=1S/C11H10O3/c1-6-2-7-3-9-10(14-5-13-9)4-8(7)11(6)12/h3-4,6H,2,5H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



University of Illinois

Curated by ChEMBL


Assay Description
Inhibition of acetylcholinesterase.


J Med Chem 35: 584-9 (1992)


Article DOI: 10.1021/jm00081a022
BindingDB Entry DOI: 10.7270/Q20G3J3J
More data for this
Ligand-Target Pair