BDBM50008858 2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-acetamide; hydrochloride::CHEMBL539246

SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2occc12

InChI Key InChIKey=JMBYBVLCYODBJQ-GAIPOIILSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008858   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008858(2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...)
Affinity DataKi:  0.830nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity,determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008858(2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-...)
Affinity DataKi:  1.26E+3nMAssay Description:Compound was evaluated for the Opioid receptor mu 1 affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed