BDBM50008978 (+/-)-(2-Methyl-8-phenyl-7,8-dihydro-6H-9-oxa-1,3a-diaza-cyclopenta[a]naphthalen-3-yl)-acetonitrile::(2-Methyl-8-phenyl-7,8-dihydro-6H-9-oxa-1,3a-diaza-cyclopenta[a]naphthalen-3-yl)-acetonitrile::7H-8,9-dihydropyrano[2,3c]imidazo[1,2-a]pyridine::CHEMBL296482

SMILES Cc1nc2c3OC(CCc3ccn2c1CC#N)c1ccccc1

InChI Key InChIKey=YRPXTKFOVDZRBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008978   

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008978((+/-)-(2-Methyl-8-phenyl-7,8-dihydro-6H-9-oxa-1,3a...)
Affinity DataIC50:  92nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50008978((+/-)-(2-Methyl-8-phenyl-7,8-dihydro-6H-9-oxa-1,3a...)
Affinity DataIC50:  64nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed