BindingDB logo
myBDB logout

BDBM50008988 2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-one::CHEMBL3144581::CHEMBL8082

SMILES: C[C@@H](c1cccc2ccccc12)n1[nH]c2ccccc2c1=O

InChI Key: InChIKey=AOOSKFQNKDXJCS-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008988   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase


(RAT)
BDBM50008988
PNG
(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Show SMILES C[C@@H](c1cccc2ccccc12)n1[nH]c2ccccc2c1=O
Show InChI InChI=1S/C19H16N2O/c1-13(15-11-6-8-14-7-2-3-9-16(14)15)21-19(22)17-10-4-5-12-18(17)20-21/h2-13,20H,1H3/t13-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



ICI Pharma

Curated by ChEMBL


Assay Description
In vitro inhibition of PGE-2 production was measured in rat blood


J Med Chem 34: 1028-36 (1991)


Article DOI: 10.1021/jm00107a023
BindingDB Entry DOI: 10.7270/Q28G8MXH
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50008988
PNG
(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Show SMILES C[C@@H](c1cccc2ccccc12)n1[nH]c2ccccc2c1=O
Show InChI InChI=1S/C19H16N2O/c1-13(15-11-6-8-14-7-2-3-9-16(14)15)21-19(22)17-10-4-5-12-18(17)20-21/h2-13,20H,1H3/t13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



ICI Pharma

Curated by ChEMBL


Assay Description
In vitro inhibition of LTB4 production was measured in rat blood


J Med Chem 34: 1028-36 (1991)


Article DOI: 10.1021/jm00107a023
BindingDB Entry DOI: 10.7270/Q28G8MXH
More data for this
Ligand-Target Pair