BDBM50009000 2-Benzyl-1,2-dihydro-indazol-3-one::CHEMBL1984519

SMILES O=c1n(Cc2ccccc2)[nH]c2ccccc12

InChI Key InChIKey=IBMDKBAGSDBZIJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009000   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009000(2-Benzyl-1,2-dihydro-indazol-3-one | CHEMBL1984519)
Affinity DataIC50: 360nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009000(2-Benzyl-1,2-dihydro-indazol-3-one | CHEMBL1984519)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009000(2-Benzyl-1,2-dihydro-indazol-3-one | CHEMBL1984519)
Affinity DataEC50:  8.91E+4nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed