BDBM50009009 2-(3-Phenyl-propyl)-1,2-dihydro-indazol-3-one::CHEMBL3144578

SMILES O=c1n(CCCc2ccccc2)[nH]c2ccccc12

InChI Key InChIKey=ZTUNGCGUHQENHO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009009   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009009(2-(3-Phenyl-propyl)-1,2-dihydro-indazol-3-one | CH...)
Affinity DataIC50:  540nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009009(2-(3-Phenyl-propyl)-1,2-dihydro-indazol-3-one | CH...)
Affinity DataEC50: >3.96E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009009(2-(3-Phenyl-propyl)-1,2-dihydro-indazol-3-one | CH...)
Affinity DataIC50:  3.80E+3nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed