BDBM50009073 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide::CHEMBL603::ZAFIRLUKAST::cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate::cyclopentyl 3-[2-methoxy-4-(2-methylphenylsulfonylcarbamoyl)benzyl]-1-methyl-1H-indol-5-ylcarbamate

SMILES: Cc1ccccc1S(=O)(=O)NC(=O)c2ccc(c(c2)OC)Cc3cn(c4c3cc(cc4)NC(=O)OC5CCCC5)C

InChI Key: InChIKey=YEEZWCHGZNKEEK-UHFFFAOYSA-N

Data: 16 KI  35 IC50  1 Kd  8 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 60 hits for monomerid = 50009073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug and toxin extrusion protein 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Beta-1/Beta-2/Beta-3 adrenergic receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Exportin-1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug and toxin extrusion protein 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Rat)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.84E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.06E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kelch-like ECH-associated protein 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/bile acid cotransporter (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 2 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/bile acid cotransporter (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/bile acid cotransporter (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Human)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Guinea pig)	BDBM50009073 (cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair