BDBM50009179 CHEMBL3238370

SMILES Cn1c(CN2C(=O)CN(C2=O)c2cccc(c2)C#N)cc2cnc(nc12)C(=O)N[C@@H](CCCCN)C#N

InChI Key InChIKey=WHZQYKIIFMNEQT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009179   

TargetPlasminogen(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009179(CHEMBL3238370)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-LyspNA (S-2251) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009179(CHEMBL3238370)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human plasma urokinase using Glu-Gly-Arg-pNA (S-2444) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50009179(CHEMBL3238370)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human plasma kallikerin using H-D-Phe-Pro-Arg-pNA (S-2302) peptide as substrate assessed as reduction of enzyme hydrolytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed