BDBM50009535 (CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol::2-[6-Amino-2-(2-cyclohex-1-enyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL314313

SMILES Nc1nc(NCCC2=CCCCC2)nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=SLUGAKUMOFIJEH-IKYDMHQPSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009535   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataIC50:  2.69E+3nMAssay Description:Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataIC50:  13nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataEC50:  2.20nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataEC50:  2.29E+4nMAssay Description:In vitro prolonging of the stimulus-QRS interval in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed