BDBM50009561 (E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol::2-Methoxy-5-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::2-methoxy-5-(3,4,5-trimethoxystyryl)phenol::2-methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol::CHEMBL36455::E-Combretastatin A-4::trans-2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol::trans-combretastatin A-4

SMILES COc1ccc(\C=C\c2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=HVXBOLULGPECHP-AATRIKPKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50009561   

TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50:  5.00E+4nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50: >5.00E+4nMAssay Description:Ability to inhibit Tubulin polymerization in Bovine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of tubulin polymerization upon incubation for 20 min at 30 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50009561((E)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol | 2...)
Affinity DataIC50:  680nMAssay Description:Inhibition of bovine brain tubulin polymerization incubated for 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed